Perotech Sciences

Vibration and Noise Monitoring

Facility Noise & Vibration Monitoring

 

Features

  • Detecting Turner Scientificdamaging levels of vibration in the animal is now possible with our revolutionary new device and app, VibraSearch.

  • Connect via Bluetooth wireless technology to each device in range.

  • Toggle effortlessly between measurement scales and display data with ease.

  • Clear visualization of safe and harmful levels.

  • Simply place the VibraSearch device inside a cage or on a rack and connect via Bluetooth wireless technology to the VibraSearch app on any IOS device.

Wireless

  • As small as a deck of playing cards, the VibraSearch device allows users to move from room to room with ease and without the mess of tangled cords.

  • Magnets mounted on the exterior aid in attaching the device directly to metal.

Mobility

  • The app displays accurate and easy-to-interpret vibration data, and also indicates whether the vibration level is safe or is at a level known to be harmful to animal models.

Data Collection

  • Vibration in the animal facility has been identified as an animal welfare concern as well as a potential experimental confound.

  • Problematic vibration can result from the use of Individually Ventilated Caging systems (IVCs), room-to-room transport, facility construction, nearby train lines, and many other sources.

  • Exposure to chronic vibration has been linked to chronic stress response in mice and rats such as cortisol increases, decreased pregnancy rates, and changes in the cardiovascular function.

  • Vibration levels less than 0.05g in rats and mice do not cause reliable changes in cardiovascular functions or in homeostatic cortisol levels, whereas a number of studies in both animal and human literature suggests that exposure greater than 0.05g can cause these significant changes.

  • Incidentally, the same exposure level is used for defining the human occupational safety exposure limit of vibration to 0.05g

  • To alert facility managers of potentially harmful vibration levels, VibraSearch sends alerts when vibration levels reach 0.05g  higher.

Why it Matters

  • Vibration in the animal facility has been identified as an animal welfare concern as well as a potential experimental confound.

  • Problematic vibration can result from the use of Individually Ventilated Caging systems (IVCs), room-to-room transport, facility construction, nearby train lines, and many other sources.

  • Exposure to chronic vibration has been linked to chronic stress response in mice and rats such as cortisol increases, decreased pregnancy rates, and changes in the cardiovascular function.

  • Vibration levels less than 0.05g in rats and mice do not cause reliable changes in cardiovascular functions or in homeostatic cortisol levels, whereas a number of studies in both animal and human literature suggests that exposure greater than 0.05g can cause these significant changes.

  • Incidentally, the same exposure level is used for defining the human occupational safety exposure limit of vibration to 0.05g

  • To alert facility managers of potentially harmful vibration levels, VibraSearch sends alerts when vibration levels reach 0.05g higher.

  • Turner Scientific provides noise and vibration measurement services for biomedical research facilities and they wanted a way to allow their customers to measure vibration data regularly using their own devices.  These minute vibrations have been associated with changes in the behavior of animals at research facilities and laboratories. They worked with Studio M-Five to engineer a solution that would allow for researchers to collect their own vibration data to improve the welfare of the animals in the facilities, thus leading to more accurate test results. VibraSearch was designed to empower researchers, veterinarians or any lab staff to collect their own vibration data using a custom-developed Bluetooth® LE device. The VibraSearch device accurately detects minute vibration data to the scale of +/- 2g along the X, Y, and Z axis using an accelerometer.  These data are displayed on the VibraSearch app in the form of a bar graph as well as a numerical value.  Using these data, the researcher can determine if the animal is subject to any unsafe vibration levels.

History

  • 1Atanasov, N. A., Sargent, J. L., Parmigiani, J. P., Palme, R., & Diggs, H. E. (2015). Characterization of train-induced vibration and its effect on fecal corticosterone metabolites in mice. Journal of the American Association for Laboratory Animal Science, 54(6), 737-744.
  • 2Hurst, K., & Litwak, K. N. (2012). Accelerative forces associated with routine in-house transportation of rodent cages. Journal of the American Association for Laboratory Animal Science: JAALAS, 51(5), 544.
  • 3ISO 2631-1:1997 Mechanical vibration and shock — Evaluation of human exposure to  whole-body vibration — Part 1: General requirements.
  • 4Li, Y., Rabey, K. N., Schmitt, D., Norton, J. N., & Reynolds, R. P. (2015).  Characteristics of vibration that alter cardiovascular parameters in mice. Journal of the American Association for Laboratory Animal Science: JAALAS, 54(4), 372.
  • 5Logge, W., Kingham, J., & Karl, T. (2014). Do individually ventilated cage systems generate a problem for genetic mouse   model research?. Genes, Brain and Behavior, 13(7), 713-720.
  • 6Norton, J. N., Kinard, W. L., & Reynolds, R. P. (2011). Comparative vibration levels perceived among species in a  laboratory animal facility. Journal of the American Association for Laboratory Animal Science, 50(5), 653-659.
  • 7Raff, H., Bruder, E. D., Cullinan, W. E., Ziegler, D. R., & Cohen, E. P. (2011). Effect of animal facility construction on basal hypothalamic-pituitary-adrenal and reninaldosterone activity in the rat. Endocrinology, 152(4), 1218-1221.
  • Monitor noise and ultrasonic noise in your vivarium with VivAlarm, the first 24-hour monitoring system created specifically for the animal research environment.

  • VivAlarm provides data logging for up three weeks, which can be used to strengthen the credibility of your research by ensuring that your animals are not being exposed to stress-inducing auditory stimuli for extended periods of time.

  • VivAlarm is a great way to become aware of unknown auditory stressors that humans are not able to perceive, which could likely be the cause of behavioural changes in the animals.

Features

  • The 24-hour monitoring system can send alerts via text or email to facility directors, Pls, or construction personnel.

  • Alerts can also send directly to OSL through VPN (Virtual Private Network, where we can provide “smart” monitoring and minimize the stress of false alarms.

Alert System

  • The VivAlarm system collects and logs noise data for up to three weeks, allowing for review of daily and weekly noise patterns and distrubances.

Data Logging

  • Construction/remodeling

  • Individually vented caging systems

  • Fluorescent lighting

  • Motion detectors

  • Cage wash stations

For Use in Vivariums With:

  • Noise and ultrasonic noise are present in all research animal facilities and laboratories. These acoustic stimuli have been associated with changes in breeding and behavior, as well as a number of other physiological effects involving cardiovascular and stress pathways (e.g., see Turner et al, 2005 for a review). The result is that such stimuli can be confounds for ANY area of biomedical research using animal models because they add variability to measurements, resulting in greater statistical ambiguity in our research and the need for more animals.

2005, Turner, J.G., Parrish, J., Hughes, L.F., Toth, L.A., & Caspary, D.M. "Hearing in Laboratory Animals: Strain Differences and Non-Auditory Affects of Noise." Comparative Medicine, 55, 12-23.


Vibration in Biomedical Research FacilitiesTurner Scientific

  labview_600x709Turner Scientific brings 20 years of experience with noise and vibration in animal facilities to work for you as the first full-service firm focused on noise, ultrasonic noise and vibration. Turner Scientific is proud to introduce the following services:

  • Noise and vibration consulting for new construction or remodels

  • On-site noise and vibration measurements

  • Educational programming for staff (on-site and web-based)

  • 24-hour monitoring services for sensitive models or during construction

  • Documenting that equipment is noise and vibration free

  • Specialized equipment for sale or rent (daily, weekly, monthly)

  • New, Noise and vibration monitoring in vivarium spaces that can send instant notifications about problems to facility directors, study PI, or to OtoScience Labs’ central monitoring service.

  • Why should this matter to you? Noise, ultrasonic noise, and vibration are present in all research animal facilities and laboratories. These acoustic and vibratory stimuli have been associated with changes in breeding and behavior, as well as a number of other physiological effects involving cardiovascular and stress pathways (e.g., see Turner et al, 2005 for a review). The result is that such stimuli can be confounds for ANY area of biomedical research using animal models because they add variability to measurements, resulting in greater statistical ambiguity in our research and the need for more animals.

We recommend that every animal facility measure noise, ultrasonic noise and vibration at least annually, anytime new equipment or construction is introduced, and anytime facility or research personnel see unexpected changes in breeding, behavior or health. Especially sensitive models or work that could be impacted by noise and vibration should use our 24-hour monitoring service. Facilities need to begin measuring and controlling for noise, ultrasonic noise and vibration with the same care that is given to light, water, food, and air quality.

Quad CaptureUltrasonic noise is of special concern because it is not audible by the researchers or animal caretakers and therefore is not recognized. Several places in the Guide For the Care and Use of Laboratory Animals (8th ed.) draw our attention to this. For example, in Chapter 3 the Guide states that “Many species can hear sound frequencies inaudible to humans…….and materials that produce noise in the hearing range of nearby animals can thus become an uncontrolled variable for research experiments and should therefore be carefully considered (Turner et al. 2007; Willott 2007).” Since mice, rats, and most other models hear very well in the ultrasonic range, such noise can serve as a “quiet” confound to biomedical researchers.

Not knowing what ultrasonic noise is present in the facility is analogous to not knowing when the lights are on or off! There are many sources of ultrasonic noise in biomedical research facilities and laboratories, such as fluorescent lighting, motors that run cage-changing stations or ventilated caging systems, computers, etc. Some ultrasonic noise and vibration issues can be prevented or minimized at the time of building, others (once identified) can be fixed with minimal effort.

References:

  2005, Turner, J.G., Parrish, J., Hughes, L.F., Toth, L.A., & Caspary, D.M. “Hearing in Laboratory Animals: Strain Differences and Non-Auditory Affects of Noise.” Comparative Medicine, 55, 12-23.

  2007, Turner, J.G., Bauer, C.A., & Rybak, L.P. “Noise in Animal Facilities: Why it Matters.” Journal of the American Association of Laboratory Animal Science, 46, 10-13.

  2007, Willott, J.F. “Factors affecting hearing in mice, rats, and other laboratory animals. Journal of the American Association of Laboratory Animal Science, 46, 23-7.